Dosimetric comparison study of intensity modulated radiotherapy technique (IMRT/VMAT) with three dimensional field-in-field tangents for left breast cancer irradiation

Purpose: To retrospectively compare dosimetrically three dimensional field-in-field tangents (3D F-in-F), Intensity modulated radiotherapy (IMRT) and volumetric arc therapy (VMAT) left breast irradiation plans. Materials Methods: A total of 30 patients were included in this study. All diagnosed with early–stage malignant neoplasm the prior to treatment. Patients contoured main PTV-Chest wall (PTVCW), PTV-Axilla (PTVAX), PTV-IMC (PTVIMC). Monaco treatment planning system was used create For each patient, plans created; conformal (3D-CRT), intensity (IMRT), (VMAT). The dose coverage PTVs constraints Organ-at-Risks (OARs) compared analyzed. Results: objective cover PTVs; PTVCW, PTVAX, PTVIMC V40.43Gy (95%) ≥ 95%, V38.3Gy (90%) V34.05Gy (80%) 95% respectively. Comparing PTVCW between 3D-CRT VMAT, resulted a significant difference (P= 0.003) VMAT superior for target than 3D-CRT. 45.80±0.55, 45.96±0.73, 45.58±0.63 3D-CRT, IMRT, PTVIMC,